First proof-of-concept study showing that short-term blockade of calprotectin improves heart function after myocardial infarction

The research team of Dr. Alexandru Schiopu at Lund University published the first proof-of-concept study showing that short-term blockade of calprotectin (S100A8/A9) with a small molecule therapeutic inhibits inflammation, reduces heart damage and improves heart function in mice with myocardial infarction (MI). The study has been published in the European Heart Journal, the top-ranked international journal in the cardiovascular field.

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Inhibition of inflammation by short-term S100A9 blockade improves cardiac function after myocardial infarction